Manufacturing techniques and excipients used during the formulation of oil-in-water type nanosized emulsions for medical applications

  • Tamilvanan Shunmugaperumal Associate Professor
  • Senthilkumar Sudalaimuthu Ramachandran
  • Baskar Raj
  • Raja Sekharan Thenrajan

Abstract

Medically, the oil-in-water nanosized emulsions are used mainly as delivery carriers for lipophilic drug molecules which show therapeutic activity when administered via parenteral, ocular and transdermal routes. To extract multifunctional activities, the nanosized emulsions containing neutral, anionic and cationic charges over dispersed oil droplets are designed with the help of variety of excipients especially emulsifiers. This type of decoration on the dispersed oil droplets surface allows the nanosized emulsions to be useful for drug delivery and/or drug targeting to otherwise inaccessible internal organs of human body. The aim of this review is to address the various manufacturing techniques and excipients used during the formulation of the multifunctional o/w nanosized emulsions for medical applications.
Published
2010-06-18
How to Cite
SHUNMUGAPERUMAL, Tamilvanan et al. Manufacturing techniques and excipients used during the formulation of oil-in-water type nanosized emulsions for medical applications. Journal of Excipients and Food Chemicals, [S.l.], v. 1, n. 1, p. 11-29, june 2010. ISSN 21502668. Available at: <https://ojs.abo.fi/ojs/index.php/jefc/article/view/10>. Date accessed: 27 oct. 2021.
Section
Reviews

Keywords

Nanosized emulsions; Manufacturing techniques; Excipients; Anionic; Cationic; Neutral